Pierre de la Grange

The paper identifies monocyte interactions with CD8+ T cells during tumor regression, showing their role in promoting T-cell infiltration and anti-tumor immunity.

This study identifies hnRNP C as a repressor of circRNA biogenesis in Group 3 medulloblastoma by binding Alu elements and preventing pre-mRNA circularization.

This study identifies PRPF40B as a regulator of NTRK2 alternative splicing, influencing TRKB isoform production and impacting neuronal differentiation and synaptic plasticity.

The paper uses multi-omics analysis to compare malignant and normal uveal melanocytes, identifying genomic instability and a BAP1 promoter deletion as key features of uveal melanoma.

This study shows that activating the JAK2-STAT3 pathway in astrocytes reduces mutant Huntingtin aggregates and improves disease outcomes in Huntington's disease models.

The paper shows that oligodendrocyte secreted factors influence hippocampal GABAergic neuron transcriptome and physiology by modulating gene expression and synaptic activity.