Jane C. Figueiredo

Obesity promotes conserved inflammatory and metabolic transcriptional programs in mouse and human colon tumors

This study identifies obesity-driven inflammatory and metabolic transcriptomic signatures in mouse and human colon tumors through integrated transcriptomic analyses.

Genetic architectures of proximal and distal colorectal cancer are partly distinct

This study identifies 13 new genetic loci specific to proximal or distal colorectal cancer subtypes, revealing partly distinct genetic architectures for these tumor locations.

Physical activity and risks of breast and colorectal cancer: A Mendelian randomization analysis

This study uses Mendelian randomization to show that higher physical activity levels are associated with lower risks of breast and colorectal cancer.