Cell BiologyScience AdvancesPeer-reviewed
Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts
Jo-Anne A M Wilson, Rachel Walters, Greg Contento…·Rachel Clare Chambers
This study shows that the TGF-β1/mTORC1 signalling axis regulates the transcriptional identity of CTHRC1+ fibroblasts in IPF, supporting mTORC1 as a therapeutic target.
3 citations