Author

Greg Contento

University College LondonORCID 0000-0002-2228-3123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Rachel Clare ChambersiD· 2 shared A. Reed· 1 shared Alexander I. WardiD· 1 shared Alison E. JohniD· 1 shared Bin LiuiD· 1 shared Delphine GuillotiniD· 1 shared Elizabeth Pyman· 1 shared Gisli R. JenkinsiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Rachel Clare ChambersORCID

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2 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedSep 2, 2026

Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts

Jo-Anne A M Wilson, Rachel Walters, Greg Contento…·Rachel Clare Chambers

This study shows that the TGF-β1/mTORC1 signalling axis regulates the transcriptional identity of CTHRC1+ fibroblasts in IPF, supporting mTORC1 as a therapeutic target.

3 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsbioRxivPreprintJan 23, 2026

Targeting AKAP13 RhoGEF activity ameliorates pro-fibrotic phenotypes driven by the IPF associated AKAP13 risk variant

Bin Liu, James Michael May, Greg Contento…·Alison E. John

This study shows that an AKAP13 genetic variant promotes fibrosis by altering epithelial signaling, and inhibiting AKAP13's RhoGEF activity reduces fibrotic markers in IPF models.

DOI 10.64898/2026.01.21.700846

humanbulk RNA-seq

𝕏 PostBluesky