Whole genome sequencing with AVITI and NovaSeq X Plus reveals comparable performance with contextual biases
Pontus Höjer, Johannes Alneberg, Pär Lundin, Tom Martin, Julia Hauenstein, Helena Fällmar, Magnus Lindell, Christian Natanaelsson, Susana Häggqvist, Adam Ameur, Jessica Nordlund, Robert Månsson Welinder
The paper compares variant calling performance between Illumina NovaSeq X Plus and Element AVITI sequencing platforms using whole genome sequencing of human tumor cell lines, finding comparable results with minor differences in specific genomic contexts.
NAR Genomics and Bioinformatics · Mar 27, 2026Peer-reviewedGenomics