Molecular BiologybioRxivPreprint
RNA-triggered protein cleavage and cell death by the RNA-guided type III-E CRISPR-Cas nuclease-protease complex
Kazuki Kato, Sae Okazaki, Cian Schmitt-Ulms…·Hiroshi Nishimasu
This study characterizes the RNA-guided nuclease-protease complex Cas7-11-Csx29, showing target RNA binding activates Csx29 to cleave Csx30, leading to cell death.
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