Author

Derk Amsen

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-2491-4566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Ann M. G. L. De MazièreiD· 1 shared Anna KnoliD· 1 shared Brenda RaudiD· 1 shared Cornelieke E. G. M. Pals· 1 shared Edward Corrigan· 1 shared Enric MocholíiD· 1 shared Jan van der BeekiD· 1 shared Judith KlumpermaniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Ann M. G. L. De MazièreORCID

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1 paper

Recent·Most cited

CD4+ T cell activation is dependent on a novel form of ULK1/2-independent autophagy

Edward Corrigan, Jan van der Beek, Brenda Raud, Julia Oliverira Lima, Ann M. G. L. De Mazière, Anna Knol, Cornelieke E. G. M. Pals, Derk Amsen, Judith Klumperman, Enric Mocholí, Paul James Coffer

This study identifies a novel form of autophagy in CD4+ T cells that is independent of ULK1/2 and occurs alongside mTORC1 activation, supporting proliferation and cytokine production.

bioRxiv · May 1, 2026 · PreprintCell Biology