Sylvain Williams

This study shows that hippocampal reward representations become predictive of reward over time as mice learn a reward-based task.

This study shows that O-LM interneurons adapt their activity based on navigational reference frames, while VIP interneurons are more influenced by familiarization.

This study investigates neural reactivation during REM sleep in mice, finding that novel and anxiety-related experiences shape distinct patterns of hippocampal assembly reactivation and sequence replay.

The paper develops an unsupervised model to decode elapsed time and distance from neural activity in freely moving mice, showing spatiotemporal information is a mix of idiothetic and allocentric signals.

This study uses optogenetics to disrupt theta rhythms in mice and shows that theta is essential for working memory retrieval but not for spatiotemporal coding.

This study shows that REM sleep stabilizes newly formed place cells through coordinated population activity in the hippocampus.

This study identifies that MS glutamate neurons encode navigationally relevant information and are essential for spatial learning in mice.

The paper identifies spatial and idiothetic coding in LS GABAergic cells, showing topographic organization and functional connectivity with hippocampal regions.

This study characterizes the electrophysiological, morphological, and input properties of VIP interneurons in the MEC of mice, revealing their sensory inputs and role in disinhibition.

The paper introduces a standardized platform for high-throughput imaging of neuronal dynamics during behavior in mice and marmosets.

This paper introduces a probabilistic framework for decoding behavior from calcium imaging data using a naive Bayesian classifier, showing it can infer behavior and predict neuronal activity from behavior.

The paper shows that hippocampal neurons in monkeys encode spatial and non-spatial features differently during two virtual navigation tasks, leading to task-specific population codes.

This study examines theta-gamma coupling dynamics during REM sleep, showing increased coupling in subicular and cortical regions and its role in memory mechanisms.

This study investigates the role of KCC2-dependent potassium efflux in 4-aminopyridine-induced epileptiform synchronization through experiments and a biophysically realistic network model.