ImmunologyJCI InsightPeer-reviewed
Long-term immune reprogramming of classical monocytes with altered ontogeny mediates enhanced lung injury in sepsis survivors
Scott J. Denstaedt, Breanna McBean, Alan P. Boyle…·Rachel L. Zemans
The paper shows that sepsis reprograms monocytes into a pro-inflammatory state and shifts their lineage toward neutrophil-like cells, increasing lung injury risk in survivors.