Bethany B. Moore

The paper shows that sepsis reprograms monocytes into a pro-inflammatory state and shifts their lineage toward neutrophil-like cells, increasing lung injury risk in survivors.

This study shows that kynurenine modulates AHR signaling in specific pulmonary cell types, with pathogenic effects requiring cell-cell interactions, not isolated cell responses.

This paper shows that immunomodulatory nanoparticles reprogram monocytes to resolve pulmonary fibrosis by inducing antifibrotic immune activation and ECM degradation.

SKiM-GPT evaluates biomedical hypotheses by combining literature-based discovery with large language models to assess hypothesis validity using retrieved PubMed abstracts.

This study shows that Toxoplasma gondii's PLP1 protein drives cytokine release syndrome by inducing dysregulated immune responses, leading to lethal inflammation during acute infection.

This study identifies CD103+ dendritic cell-fibroblast crosstalk via TLR9 and AHR signaling as a driver of lung fibrosis in IPF, showing that inhibiting AHR signaling reduces fibrosis.

This paper presents a single-cell RNA sequencing atlas of the human uterus, identifying 39 cell subtypes and proposing a consensus annotation system, while highlighting dynamic changes and potential progenitor cells across menstrual cycle phases.

This study shows that heat-killed Lactobacillus johnsonii reduces herpesvirus-induced pulmonary fibrosis in HCT mice by increasing PD-L1 on dendritic cells, which suppresses Th17 cell IL-17A.