Katsuo Kurabayashi

Patient-Derived Synovium-on-a-Chip Recapitulates Disease and Treatment Response and Permits Study of Resistance

This paper develops a patient-derived synovium-on-a-chip model to study RA disease and treatment response, finding that it correlates with clinical outcomes and identifies ECM signaling as a resistance mechanism.

Risk-Aware Control for Insulin Delivery via Nonlinear MPC with Safety Barrier Functions and Probabilistic Learning of Uncertainties

This paper develops a risk-aware control framework for insulin delivery that uses nonlinear MPC with safety barrier functions and probabilistic learning to manage glucose levels safely in diabetes management.

High Spatiotemporal Imaging of Protein Secretion During Cell to Cell Communication via Integrative Biosensing Nanoplasmonic Array

This paper introduces a nanoplasmonic array for real-time imaging of protein secretion, revealing spatiotemporal dynamics of cell-cell communication.

High-temporal-resolution point-of-care multiplex biomarker monitoring in small animals using microfluidic digital ELISA

This paper develops a microfluidic digital ELISA platform for rapid, high-temporal-resolution biomarker monitoring in small animals using whole blood, demonstrating its utility in a murine sepsis model.

Optimized gene expression from bacterial chromosome by high-throughput integration and screening

The paper optimizes gene expression in bacterial chromosomes through random integration and high-throughput screening, achieving high isobutanol production in Escherichia coli.

Syntrophic co-culture amplification of production phenotype for high-throughput screening of microbial strain libraries

This paper introduces SnoCAP, a method for high-throughput screening of microbial strain libraries by amplifying production phenotypes through syntrophic co-culture, demonstrating its effectiveness in identifying efficient producers of target molecules.