Molecular BiologybioRxivPreprint
Synuclein alpha accumulation mediates podocyte injury in Fabry nephropathy
Ahmed Abed, Fabian Braun, Dominik Sellung…·TB Huber
This study identifies alpha-synuclein accumulation as a mediator of podocyte injury in Fabry disease, showing that targeting SNCA improves lysosomal function beyond enzyme replacement therapy.
DOI 10.1101/2021.12.17.473164