Florian Grahammer

This study uses cryo-electron tomography to analyze structural changes in podocytes during anti-nephrin-mediated kidney disease progression.

This study localizes albumin in kidney tissue using correlative super-resolution light and electron microscopy to map its distribution and quantify concentration gradients across the filtration barrier.

This study uses single-cell RNA sequencing to identify a mechanosensitive MRTF-SRF pathway in early diabetic nephropathy, validated in human datasets and ex vivo experiments.

This study identifies alpha-synuclein accumulation as a mediator of podocyte injury in Fabry disease, showing that targeting SNCA improves lysosomal function beyond enzyme replacement therapy.