Behzad Najafian

This study isolates podocyte mitochondria from mice to show they have higher respiratory capacity than tubule mitochondria, with age- and sex-dependent differences.

This study uses mouse models to investigate mitochondrial metabolism in specific kidney tubular cell types and finds differences in mitochondrial function under fasting conditions.

This study identifies alpha-synuclein accumulation as a mediator of podocyte injury in Fabry disease, showing that targeting SNCA improves lysosomal function beyond enzyme replacement therapy.