Kennosuke Ichikawa

This study establishes a long-term culture system for rock dove primordial germ cells, enabling germline manipulation and conservation applications.

This study shows that cell-matrix interactions regulate self-renewal and undifferentiated state of chicken primordial germ cells, with excessive interactions causing somatic conversion.

This study uses RNA-seq to analyze gene expression in male and female avian primordial germ cells, revealing sex-biased gene expression and suggesting a combination of cell-autonomous and somatic regulation in sex determination.