Author
Universitat de ValènciaORCID 0000-0002-2532-0487Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
F. Sanz, Cristina Solana‐Manrique, Nuria Paricio
This study identifies vincamine as a potential therapeutic for Parkinson's disease by showing it reduces oxidative stress and motor defects in Drosophila and human cell models.
bioRxiv · Dec 28, 2022 · PreprintNeuroscience
F. Sanz, Cristina Solana‐Manrique, Joaquín Lilao‐Garzón, Yeray Brito‐Casillas, Silvia Muñoz Descalzo, Nuria Paricio
This study investigates the link between Parkinson's disease and diabetes mellitus using Drosophila models, finding that T2DM may increase PD risk and that metformin could prevent PD onset in T2DM models.
bioRxiv · Feb 18, 2022 · PreprintNeuroscience
Cristina Solana‐Manrique, F. Sanz, Isabel Torregrosa, Martina Palomino‐Schätzlein, Carolina Hernández-Oliver, Antonio Pineda‐Lucena, Nuria Paricio
This study investigates metabolic changes in a Drosophila Parkinson's disease model with DJ-1 deficiency, identifying altered pathways and potential therapeutic targets.
Cells · Jan 19, 2022Peer-reviewedNeuroscience
Cristina Solana‐Manrique, Verónica Muñoz-Soriano, F. Sanz, Nuria Paricio
The paper shows that SERCA activity is reduced in DJ-1 mutant flies and human cells due to oxidative modification, and that activating SERCA can restore PD-related phenotypes.
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · Apr 21, 2021Peer-reviewedNeuroscience
Cristina Solana‐Manrique, F. Sanz, Edna Ripollés, María Carmen Bañó, Josema Torres, Verónica Muñoz-Soriano, Nuria Paricio
This study shows that DJ-1 deficiency in Drosophila and human cell models of Parkinson's disease increases glycolytic enzyme activity, and that FDA-approved drugs can mitigate PD-related phenotypes by enhancing glycolysis.
Free Radical Biology and Medicine · Jul 26, 2020Peer-reviewedNeuroscience