Author

Ying Margie Tang

Rutgers New Jersey Medical SchoolORCID 0000-0002-2532-3477Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 4 Approach:statistical model· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1

Frequent Co-Authors

Edward J. YurkowiD· 2 shared Melissa B. RogersiD· 2 shared Stephen Y. ChaniD· 2 shared Tapan A. Shah· 2 shared Haodi WuiD· 1 shared Jimin YangiD· 1 shared John SembratiD· 1 shared Joseph C. WuiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Edward J. YurkowORCID

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Author profile →

4 papers

Recent·Most cited

Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension

Rashmi J. Rao, Jimin Yang, Siyi Jiang, Wadih El-Khoury, Neha Hafeez, Satoshi Okawa, Yi‐Yin Tai, Ying Margie Tang, Yassmin Al Aaraj, John Sembrat, Stephen Y. Chan

This study shows IFI16, regulated by m6A modification, drives inflammatory endothelial changes in pulmonary arterial hypertension.

American Journal of Physiology-Lung Cellular and Molecular Physiology · Dec 10, 2024Peer-reviewedCell Biology

Mitigation of Stress-induced Structural Remodeling and Functional Deficiency in iPSC-CMs with PLN R9C Mutation by Promoting Autophagy

Qi Yu, Robert J. Barndt, Yawei Shen, Karim Sallam, Ying Margie Tang, Stephen Y. Chan, Joseph C. Wu, Qing Liu, Haodi Wu

This study investigates how the PLN R9C mutation affects iPSC-CMs and shows that promoting autophagy can mitigate stress-induced structural and functional defects in these cells.

bioRxiv · Apr 17, 2024 · PreprintMolecular Biology

MicroRNA Profiles in Calcified and Healthy Aorta Differ: Therapeutic Impact of miR-145 and miR-378

Ying Margie Tang, Tapan A. Shah, Edward J. Yurkow, Melissa B. Rogers

This study identifies miR-145 and miR-378 as miRNAs that reduce aortic calcification in Klotho mice by repressing BMP signaling.

Physiological Genomics · Sep 21, 2020Peer-reviewedMolecular Biology

Post-Transcriptional Bone Morphogenetic Protein 2 (BMP2) Gene Regulation in Aorta

Tapan A. Shah, Ying Margie Tang, Edward J. Yurkow, Melissa B. Rogers

This study investigates the role of an ultra-conserved sequence in Bmp2 mRNA regulation, showing sex- and disease-specific effects on BMP signaling and calcification in mouse aortas.

bioRxiv · Aug 15, 2019 · PreprintMolecular Biology