Author

Yassmin Al Aaraj

University of PittsburghORCID 0000-0002-3252-8606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Neha HafeeziD· 2 shared Rashmi J. Rao· 2 shared Satoshi OkawaiD· 2 shared Siyi JiangiD· 2 shared Stephen Y. ChaniD· 2 shared Yi‐Yin TaiiD· 2 shared Aaron B. WaxmaniD· 1 shared Amy WebbiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Neha HafeezORCID

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2 papers

Recent·Most cited

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Lloyd D. Harvey, Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly, Wei Sun, Chen-Shan Chen Woodcock, Sanya Arshad, Miranda K. Culley, Wadih El Khoury, Rong Xie, Yassmin Al Aaraj, Jingsi Zhao, Neha Hafeez, , Stephen Y. Chan

The paper identifies NCOA7's role in lysosomal function and inflammatory sterol metabolism in PAH, showing its deficiency exacerbates disease through oxysterol/bile acid generation.

Science · Jan 23, 2025Peer-reviewedPhysiology

Post-transcriptional regulation of IFI16 promotes inflammatory endothelial pathophenotypes observed in pulmonary arterial hypertension

Rashmi J. Rao, Jimin Yang, Siyi Jiang, Wadih El-Khoury, Neha Hafeez, Satoshi Okawa, Yi‐Yin Tai, Ying Margie Tang, Yassmin Al Aaraj, John Sembrat, Stephen Y. Chan

This study shows IFI16, regulated by m6A modification, drives inflammatory endothelial changes in pulmonary arterial hypertension.

American Journal of Physiology-Lung Cellular and Molecular Physiology · Dec 10, 2024Peer-reviewedCell Biology