Xiao‐Fan Wang

This study uses single-cell Mendelian Randomization to identify cell-type specific genetic drivers of lung cancer subtypes, finding 375 causal links and five consistent genes across tissues.

DeepScence identifies senescent cells in single-cell and spatial transcriptomics data, outperforming existing methods.

This study shows that amyloid-β precursor protein (APP) promotes tumor growth by creating an immune-exclusive tumor microenvironment through suppression of CD8+ T cell and NK cell immunity.

This study shows that neoadjuvant anti-4-1BB therapy reduces metastasis by enhancing Tint cell clonal expansion and T cell egress in TNBC.