Author

Darren B. McAffee

QB3ORCID 0000-0002-2565-4938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Organism:human· 1 Assay:imaging· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Jay T. GrovesiD· 2 shared Assame ArnobiD· 1 shared Baiyu QiuiD· 1 shared Deepti KaranduriD· 1 shared Ethan D. McSpaddeniD· 1 shared Evan R. WilliamsiD· 1 shared Hung‐Jen WuiD· 1 shared John KuriyaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Jay T. GrovesORCID

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2 papers

Recent·Most cited

Bioengineeringnpj ImagingPeer-reviewedMay 4, 2026

Machine-learning strategy for high error tolerance in image-based digital molecular assays

Darren B. McAffee, Qiang Hu, Assame Arnob…·Jay T. Groves

This study develops a machine-learning strategy to improve error tolerance in image-based nanoparticle immunoassays for field-based diagnostics.

DOI 10.1038/s44303-026-00164-9

imagingdeep learning

𝕏 PostBluesky

BioinformaticseLifePeer-reviewedSep 9, 2020

Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase

Deepti Karandur, Moitrayee Bhattacharyya, Zijie Xia…·John Kuriyan

The paper shows that the regulatory segment of CaMKII can break the oligomeric hub into smaller assemblies through binding and structural destabilization.

35 citations

humanstatistical model

𝕏 PostBluesky