Evan R. Williams

This study characterizes the structural dynamics of recombinant vaults, showing that cargo loading stabilizes their conformation for high-payload cytokine delivery in cancer therapy.

This study uses charge detection mass spectrometry to analyze DegP oligomerization states and client interactions, revealing new oligomer types and dynamic behavior.

The paper shows that the regulatory segment of CaMKII can break the oligomeric hub into smaller assemblies through binding and structural destabilization.