Breakage of the Oligomeric CaMKII Hub by the Regulatory Segment of the Kinase
Deepti Karandur, Moitrayee Bhattacharyya, Zijie Xia, Young Kwang Lee, Serena Muratcioğlu, Darren B. McAffee, Ethan D. McSpadden, Baiyu Qiu, Jay T. Groves, Evan R. Williams, John Kuriyan
The paper shows that the regulatory segment of CaMKII can break the oligomeric hub into smaller assemblies through binding and structural destabilization.
eLife · Sep 9, 2020Peer-reviewedBioinformatics