Nianjun Liu

A novel two-sample Mendelian randomization framework integrating common and rare variants: application to assess the effect of HDL-C on preeclampsia risk

This paper introduces MR-CARV, a two-sample Mendelian randomization framework integrating common and rare variants to assess the causal effect of HDL-C on preeclampsia risk, showing improved statistical power and precision.

Maternal and offspring genome-wide association study of C-reactive protein reveals limited polygenic association with gestational diabetes mellitus

This study investigates the genetic associations of early pregnancy C-reactive protein (CRP) levels with gestational diabetes mellitus (GDM) using maternal and offspring genome-wide association studies (GWAS).