Author

Wenbing Huang

Renmin University of ChinaORCID 0000-0002-2566-4159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Assay:protein structure· 2 Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:diffusion model· 1 Approach:graph neural network· 1 Organism:human· 1

Frequent Co-Authors

Jianzhu MaiD· 2 shared Rui JiaoiD· 2 shared Yang LiuiD· 2 shared Gaodeng Li· 1 shared Haowei LiniD· 1 shared Jian ZhangiD· 1 shared Jiqing ZhengiD· 1 shared Junwei CheniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioengineering

Jianzhu MaORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJun 4, 2026

Programming Biomolecular Interactions with All-Atom Generative Model

Xiangzhe Kong, Junwei Chen, Ziting Zhang…·Jianzhu Ma

This paper introduces AnewOmni, a generative model that designs biomolecules across scales by learning interaction patterns and physical constraints from 5 million complexes.

5 citations

protein structureprotein sequence

𝕏 PostBluesky

BiochemistryNature Biomedical EngineeringPeer-reviewedOct 1, 2025

✦ In-depth digest

Peptide Design through Binding Interface Mimicry

Xiangzhe Kong, Rui Jiao, Haowei Lin…·Jianzhu Ma

PepMimic, an all-atom latent diffusion model guided by a contrastive interface encoder, designs peptides mimicking known binders; 8% of tested peptides across five targets reached 10^-8M KD.

30 citationstop 1%

humanmouse

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