Author

Xiangzhe Kong

Tsinghua UniversityORCID 0009-0007-0096-2073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Approach:diffusion model· 1 Research Focus:drug response / drug discovery· 1 Approach:graph neural network· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Haowei LiniD· 1 shared Jianzhu MaiD· 1 shared Rui JiaoiD· 1 shared Ruihan GuoiD· 1 shared Wei‐Ying MaiD· 1 shared Wenbing HuangiD· 1 shared Yang LiuiD· 1 shared Zihua WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Haowei LinORCID

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1 paper

Recent·Most cited

BiochemistryNature Biomedical EngineeringPeer-reviewedOct 1, 2025

✦ In-depth digest

Peptide Design through Binding Interface Mimicry

Xiangzhe Kong, Rui Jiao, Haowei Lin…·Jianzhu Ma

PepMimic, an all-atom latent diffusion model guided by a contrastive interface encoder, designs peptides mimicking known binders; 8% of tested peptides across five targets reached 10^-8M KD.

30 citationstop 1%

humanmouse

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