Yang Liu

This paper introduces AnewOmni, a generative model that designs biomolecules across scales by learning interaction patterns and physical constraints from 5 million complexes.

The paper develops MutaPheno, a model that predicts cancer driver missense mutations using molecular features, achieving strong accuracy and outperforming existing tools.

PepMimic, an all-atom latent diffusion model guided by a contrastive interface encoder, designs peptides mimicking known binders; 8% of tested peptides across five targets reached 10^-8M KD.