BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Danicamtiv reduces myosin's working stroke but enhances contraction by activating the thin filament
Brent D. Scott, Lina Greenberg, Caterina Squarci…·Michael J. Greenberg
This study investigates danicamtiv's effects on cardiac myosin mechanics and shows it enhances contraction by altering crossbridge kinetics and thin filament activation.
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