Giuseppe Gigli

The paper identifies TUSC3 as a gatekeeper regulating glycan trimming of BMP4/Dpp to control ERQC entry and BMP signaling.

This study demonstrates the functional reconstitution of TARA76, a microbial rhodopsin, in an artificial membrane and shows its sensitivity to Na+ ions and electric field control.

This study develops a dual CAR-T therapy targeting CD33 and TIM-3 in AML, showing improved specificity and efficacy through glycosylation-modulated TIM-3 recognition.

This study identifies a mechanical regulation pathway involving Src-FAK-AMPK-GBF1 that controls cargo sorting and secretion from the Golgi in response to substrate stiffness.