Author

Sayali Joseph

University of North Carolina at Chapel HillORCID 0000-0002-2583-7080Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

Cyrus VaziriiD· 2 shared Gaith N. DrobyiD· 2 shared Jessica L. BowseriD· 2 shared Allie Mills· 1 shared Angie L. MordantiD· 1 shared Blake R. RushingiD· 1 shared Channing J. DeriD· 1 shared Di WuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Cyrus VaziriORCID

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2 papers

Recent·Most cited

TRIP13 protects pancreatic cancer cells against intrinsic and therapy-induced DNA replication stress

Jay Ramanlal Anand, Gaith N. Droby, Sayali Joseph, Urvi Patel, Xingyuan Zhang, Jeffrey A. Klomp, Channing J. Der, Jeremy E. Purvis, Samuel C Wolff, Jessica L. Bowser, Cyrus Vaziri

This study identifies TRIP13 as a key factor protecting KRAS-mutant pancreatic cancer cells from DNA replication stress and therapy-induced damage.

NAR Cancer · Jan 15, 2025Peer-reviewedCancer Biology

MAPK14/p38α Shapes the Molecular Landscape of Endometrial Cancer and promotes Tumorigenic Characteristics

Sayali Joseph, Xingyuan Zhang, Gaith N. Droby, Di Wu, Victoria Lin Bae-Jump, Scott Lyons, Angie L. Mordant, Allie Mills, Laura E. Herring, Blake R. Rushing, Jessica L. Bowser, Cyrus Vaziri

This study identifies MAPK14/p38α as critical for HGEC spheroid growth, shaping its transcriptomic, proteomic, and metabolomic landscapes and promoting tumorigenic properties.

Cell Reports · Dec 20, 2024Peer-reviewedCancer Biology