Paul W. Huber

Synonymous codon substitutions regulate transcription and translation of an upstream gene

The paper shows that synonymous codon substitutions in E. coli can upregulate an upstream gene through cryptic transcription, challenging the view that synonymous mutations have no phenotypic effects.

Remnants of the Balbiani body are required for formation of RNA transport granules in Xenopus oocytes

The paper shows that mitochondria in Balbiani body remnants generate ATP needed for RNA transport granule formation in Xenopus oocytes.

A Deficiency in SUMOylation Activity Disrupts Multiple Pathways Leading to Neural Tube and Heart Defects in Xenopus Embryos

This study shows that reduced SUMOylation activity in Xenopus embryos causes neural tube and heart defects by disrupting specific gene pathways.