Author

Taylor J. Lundgren

University of Notre DameORCID 0000-0002-3375-7283Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Taylor J. Lundgren1 paper · Oklahoma Medical Research Foundation

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew M. ChampioniD· 2 shared Patricia L. ClarkiD· 2 shared Anabel RodrígueziD· 1 shared Gabriel S. WrightiD· 1 shared Jun LiiD· 1 shared McKenze J. MossiD· 1 shared Paul W. HuberiD· 1 shared Scott EmrichiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Matthew M. ChampionORCID

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2 papers

Recent·Most cited

A Fit for Purpose Approach to Evaluate Detection of Amino Acid Substitutions in Shotgun Proteomics

Taylor J. Lundgren, Patricia L. Clark, Matthew M. Champion

The paper evaluates the detection of amino acid substitutions in shotgun proteomics by creating a ground-truth library using mixed bacterial proteomes and identifies sources of bias in substitution identification.

Journal of Proteome Research · Mar 13, 2024Peer-reviewedBioinformatics

Synonymous codon substitutions regulate transcription and translation of an upstream gene

Anabel Rodríguez, Gabriel S. Wright, Taylor J. Lundgren, McKenze J. Moss, Jun Li, Tijana Milenković, Paul W. Huber, Matthew M. Champion, Scott Emrich, Patricia L. Clark

The paper shows that synonymous codon substitutions in E. coli can upregulate an upstream gene through cryptic transcription, challenging the view that synonymous mutations have no phenotypic effects.

bioRxiv · Aug 5, 2022 · PreprintMolecular Biology