Erliang Zeng

Methylation quantitative loci analysis in nonsyndromic orofacial clefts

The paper identifies methylation quantitative loci (meQTLs) associated with nonsyndromic orofacial clefts, linking genetic variants to epigenetic changes that may explain missing heritability.

Epigenetic Signatures in Monozygotic and Dizygotic Twins Discordant for Orofacial Clefts

The paper identifies differentially methylated CpG sites in twins discordant for NSCL/P, linking them to retinoic acid signaling and chromatin regulation.

New paradigm of CRISPR spacerome for classification of global Escherichia coli lineages

The paper identifies a conserved CRISPR spacerome signature across globally distributed E. coli strains, suggesting its potential as a marker for epidemiological tracking.

DeepBioSim: Efficient and Versatile Methods for Microbiome Data Simulation with Minimal Statistical Assumptions

DeepBioSim generates realistic microbiome datasets using deep learning, without strong assumptions or phylogenetic input, and can also simulate single-organism omics profiles.

Metatranscriptomic analysis reveals toxin-antitoxin system shifts in caries-associated oral microbiomes

The paper analyzes metatranscriptomic data to identify condition-specific toxin-antitoxin system expression in oral microbiomes across health and caries states.

Gene network module changes associated with the vertebrate fin to limb transition

This study identifies gene network module changes during the vertebrate fin to limb transition by comparing zebrafish and mouse gene networks.

Integration of anatomy ontology data with protein-protein interaction networks improves the candidate gene prediction accuracy for anatomical entities

The paper integrates anatomy ontology data with PPI networks to improve candidate gene prediction accuracy for anatomical entities in zebrafish and mouse.

A Deficiency in SUMOylation Activity Disrupts Multiple Pathways Leading to Neural Tube and Heart Defects in Xenopus Embryos

This study shows that reduced SUMOylation activity in Xenopus embryos causes neural tube and heart defects by disrupting specific gene pathways.

Temporal Small RNA Expression Profiling Under Drought Reveals a Potential Regulatory Role of snoRNAs in Drought Responses of Maize

The paper profiles temporal small RNA expression in maize under drought stress and identifies snoRNAs as potential regulators of drought responses.