Author

Ines Gütgemann

University Hospital BonnORCID 0000-0002-2609-3095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Calvin KrollmanniD· 1 shared Carl Christian Kolbe· 1 shared Conny K. BaldaufiD· 1 shared Dominik Georg Friedrich WolfiD· 1 shared Eicke LatziD· 1 shared Elisabeth Tregel· 1 shared Kevin Cieslak· 1 shared Lino Lars TeichmanniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Calvin KrollmannORCID

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1 paper

Recent·Most cited

NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms

Ruth-Miriam Koerber, Calvin Krollmann, Kevin Cieslak, Elisabeth Tregel, Maria L. Saenz, Tim H. Brümmendorf, Steffen Koschmieder, Martin Grießhammer, Ines Gütgemann, Conny K. Baldauf, Thomas Fischer, Peter Brossart, Carl Christian Kolbe, Eicke Latz, Dominik Georg Friedrich Wolf, Lino Lars Teichmann

This study shows that NLRP3 inflammasome activation drives JAK2V617F mutant myeloproliferative neoplasms by promoting inflammation, platelet production, and fibrosis, and that its inhibition can reverse disease features.

Nature Communications · Nov 26, 2025Peer-reviewedCancer Biology