Jingwei Wei

This paper demonstrates that morula complementation with donor cells restores fetal kidney development in SALL1-null sheep, establishing sheep as a viable model for in vivo organ generation.

This paper generates cloned sheep lacking two xenoantigens, Gal and Neu5Gc, by knocking out their respective genes, creating a model that better mimics human immune status for preclinical testing.

The paper generates DAZL-null sheep that lack germ cells but have normal somatic cells, demonstrating the feasibility of using absolute donor germline transmitters in livestock breeding.

This study shows that targeted demethylation of H3K9me3 and H3K36me3 in bovine fibroblasts improves cloning to preimplantation embryos but not to adult survival.