Author

Alexander Jans

Renji HospitalORCID 0000-0002-2622-4278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheng LiniD· 2 shared Matthias BartneckiD· 2 shared Alan R. GorteriD· 1 shared Andrea Bonnin-MarqueziD· 1 shared Antje MohsiD· 1 shared Christian LiedtkeiD· 1 shared Christian PennersiD· 1 shared Christian WeberiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Cheng LinORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 1, 2026

The cell cycle regulator Cyclin E1 drives macrophage-associated inflammatory responses in acute immune-mediated hepatitis

Christian Penners, Cheng Lin, Alexander Jans…·Christian Liedtke

This study shows Cyclin E1 promotes macrophage-driven inflammation in acute hepatitis, independent of cell cycle changes, by regulating IRF1 and NF-κB transcriptional programs.

1 citation

mousestatistical model

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PathologybioRxivFeb 18, 2024

MicroRNA-26b protects against MASH development in mice and can be efficiently targeted with lipid nanoparticles.

Linsey J. F. Peters, Leonida Rakateli, Rosanna Huchzermeier…·Emiel P. C. van der Vorst

This paper shows that miR-26b deficiency worsens MASH in mice, and that miR-26b mimic-loaded LNPs can reverse these effects.

2 citations

mouseexperimental assay

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