Emiel P. C. van der Vorst

This study shows that Cyclin E/CDK2 deficiency enhances intestinal barrier integrity and tight junction expression in mice, contrary to initial hypotheses.

This study shows that melatonin nanoparticles reduce myeloproliferative neoplasm symptoms by targeting metabolic, inflammatory, and fibrotic pathways.

This study shows that the macrophage lipid landscape influences the immunomodulatory effects of fluoxetine, with lipid alterations affecting its anti-inflammatory potential in treatment-resistant depression.

This study identifies an HRas-Src-cortactin-Arp2/3 signaling axis that drives basement membrane rupture and breast cancer invasion through mechanical stress and cortical tension.

The paper identifies an unconventional JAK1/2-STAT3 signaling pathway in macrophage IFNγ responses, showing STAT3 activation and heterodimerization with STAT1, but limited gene regulatory contribution.

This study shows that pneumonia increases glucagon levels, which damages endothelial cells and promotes blood clotting, leading to cardiovascular issues.

This paper shows that miR-26b deficiency worsens MASH in mice, and that miR-26b mimic-loaded LNPs can reverse these effects.