PhysiologybioRxivPreprint
The DJ-1-derived peptide, ND-13, confers cardioprotection by inhibiting mitochondrial fission and preserving mitochondrial bioenergetics via the RhoA-ROCK1-Drp1 pathway
Aishwarya Prakash, Gustavo E Crespo-Avilan, Sze Jie Loo…·Derek John Hausenloy
This study shows that the DJ-1-derived peptide ND-13 reduces myocardial infarct size and preserves cardiac function by inhibiting mitochondrial fission and improving mitochondrial bioenergetics through the RhoA-ROCK1-Drp1 pathway.
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