Author

Aishwarya Prakash

Duke-NUS Medical SchoolPrimary ORCID profile (0000-0003-1441-6237 · 4 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Aishwarya PrakashiD4 papers · University of South Alabama

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Chrishan J. A. RamachandraiD· 1 shared Daniel OffeniD· 1 shared Derek John HausenloyiD· 1 shared En Ping YapiD· 1 shared Fan YuiD· 1 shared Gustavo E Crespo-AvilaniD· 1 shared Jasper ChuaiD· 1 shared Jianhong ChingiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

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10 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

Chrishan J. A. RamachandraORCID

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2 papers

Recent·Most cited

Mitochondrial activity-driven hematopoietic stem cell fate and lympho-myeloid lineage choice is first established in the aorta-gonad-mesonephros

Aishwarya Prakash, Maneesha S. Inamdar

This study shows mitochondrial activity regulates HSC fate and lineage choice during embryonic hematopoiesis in the AGM, with low mitochondrial activity promoting myeloid bias and high activity favoring lymphoid bias.

bioRxiv · Aug 25, 2024 · PreprintDevelopmental Biology

The DJ-1-derived peptide, ND-13, confers cardioprotection by inhibiting mitochondrial fission and preserving mitochondrial bioenergetics via the RhoA-ROCK1-Drp1 pathway

Aishwarya Prakash, Gustavo E Crespo-Avilan, Sze Jie Loo, En Ping Yap, Jasper Chua, Jianhong Ching, Zeng Yitong, Ying‐Hsi Lin, Whendy Contreras, Fan Yu, Shuo Cong, Linh Chi Dam, Chrishan J. A. Ramachandra, Siavash Beikoghli Kalkhoran, Shengjie Lu, , Derek John Hausenloy

This study shows that the DJ-1-derived peptide ND-13 reduces myocardial infarct size and preserves cardiac function by inhibiting mitochondrial fission and improving mitochondrial bioenergetics through the RhoA-ROCK1-Drp1 pathway.

bioRxiv · Jun 24, 2024 · PreprintPhysiology