Reference-free single-vesicle profiling of small extracellular vesicles from liquid biopsies with the PICO assay
John Atanga, Pablo Sánchez‐Martín, Siobhan King…·Irina A. Nazarenko
The paper introduces PICO, a reference-free assay for single-vesicle profiling of small extracellular vesicles, demonstrating high specificity and compatibility with clinical samples.