Author

Almudena Chaves Perez

Memorial Sloan Kettering Cancer CenterORCID 0000-0002-2663-4672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ana Marie PereaiD· 1 shared Aveline A. FillioliD· 1 shared Charles M. RudiniD· 1 shared Clemens HinterleitneriD· 1 shared Daniel A. HelleriD· 1 shared Domhnall McHughiD· 1 shared Gabriel Dessotti BarrettoiD· 1 shared Hailey V. GoldbergiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ana Marie PereaORCID

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1 paper

Recent·Most cited

Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer

Clemens Hinterleitner, Valentin J.A. Barthet, Hailey V. Goldberg, Kristen C. Vogt, Ana Marie Perea, Logan R. Hillger, Stephen B. Ruiz, Domhnall McHugh, Yu-Jui Ho, Almudena Chaves Perez, Maria Skamagki, Sara Flowers, Hannah C. Styers, Natasha Rekhtman, Xueqian Zhuang, , Scott W. Lowe

P-selectin-targeted fucoidan nanoparticles carrying Navitoclax or dBET6 deplete a senescent-like, lipid-associated macrophage subset, reverse mouse liver and lung fibrosis with less toxicity, and restore checkpoint therapy response in fibrotic tumors.

Science · Sep 24, 2026Peer-reviewedCancer Biology✦ In-depth digest