Maria Skamagki

This paper introduces Kodiak, a discrete representation learning method for scientific imaging that improves representation quality and enables interpretable, reusable concepts across domains.

P-selectin-targeted fucoidan nanoparticles carrying Navitoclax or dBET6 deplete a senescent-like, lipid-associated macrophage subset, reverse mouse liver and lung fibrosis with less toxicity, and restore checkpoint therapy response in fibrotic tumors.

This study identifies genetic mechanisms of resistance to KRAS inhibitors by using CRISPR screens to find resistance mutations and signaling rewiring in NSCLC.

The paper investigates how aging-dependent dysregulation of EXOSC2 affects cellular traits and finds that PPP2R5E, a PP2A phosphatase subunit, is a key target of EXOSC2, with this regulation maintained in stem cells and cancer.