CAIX-targeted α therapy directed against hypoxic tumor cells in combination with immune checkpoint inhibitors in a syngeneic mouse tumor model
Sylvia T.M. Wenker, Mark Konijnenberg, Daphne Lobeek…·Sandra Heskamp
This study evaluates CAIX-targeted alpha therapy (TAT) alone and in combination with immune checkpoint inhibitors (ICI) in a syngeneic mouse tumor model, showing improved survival and tumor growth inhibition.