Peter R. Wills

The paper develops substitution models that account for changes in the coding alphabet size over time, finding support for a reduced ancient alphabet in old proteins and rejecting it in young ones.

This paper introduces a probabilistic framework to detect evolutionary bursts during branching events, showing evidence in proteins, morphologies, and languages.

AARS Online provides a curated database of aminoacyl-tRNA synthetases with sequence, structure, and evolutionary information, accessible via an interactive platform.

The paper explores how Class I and II aminoacyl-tRNA synthetases discriminated between tRNA substrates, leading to the formation of the first cognate pairs and the origin of genetic coding.