Shivakumar Rajamanickam

The paper generates and validates a CRF1:Cre transgenic rat to study the role of CRF1-expressing neurons in anxiety and nociception, finding that activation of these cells increases anxiety-like behavior and pain responses.

This study identifies distinct GPe neuron subtypes using mouse lines and shows their unique roles in motor behavior and anxiety-like behavior through optogenetics and machine learning.