Suraj Cherian

This study shows that Stem Cell Factor enhances inhibition of Purkinje Cells via presynaptic Kit, leading to long-term suppression of firing and specific potentiation of basket cells.

The paper identifies cell-type-specific molecular changes in dystonia by analyzing translatomes of dSPNs and iSPNs in DRD mice, revealing glutamatergic signaling disruptions and identifying LRRK2 inhibition as a therapeutic target.

This study investigates how pathogenic LRRK2 mutations affect striatal physiology in mice, finding that R1441C causes motor learning deficits rescued by a kinase inhibitor, while G2019S does not.

This study identifies distinct GPe neuron subtypes using mouse lines and shows their unique roles in motor behavior and anxiety-like behavior through optogenetics and machine learning.

The paper identifies Npas1+-Nkx2.1+ neurons as a distinct subclass of GPe neurons and describes their role in the cortico-pallido-cortical loop.