Author

Riley W. Sinnott

University of ChicagoORCID 0000-0002-2709-1403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1

Frequent Co-Authors

Ani SolankiiD· 1 shared Anitha P. GovindiD· 1 shared Bryan C. DickinsoniD· 1 shared William N. GreeniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperSynthetic Biology

Ani SolankiORCID

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1 paper

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedFeb 1, 2026

Engineering a human-based translational activator for targeted protein expression restoration

Riley W. Sinnott, Ani Solanki, Anitha P. Govind…·Bryan C. Dickinson

This paper develops a human-based translational activator to restore protein expression in a Dravet syndrome mouse model, showing improved survivability and seizure threshold.

3 citationstop 4%

mouseexperimental assay

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