JoAnne Engebrecht

This study shows that in C. elegans male spermatogenesis, crossover-promoting factors can recruit to chromosomes without SPO-11 activity, indicating weakened crossover control compared to hermaphrodite oogenesis.

This study shows that HSR-9, the C. elegans ortholog of 53BP1, regulates meiotic recombination and X chromosome segregation, with both conserved and unique functions compared to somatic cells.

This paper investigates the role of BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in C. elegans, finding both ligase-dependent and independent functions.

This paper describes a method to isolate C. elegans males by degrading DPY-27, enabling molecular and biochemical analyses of male-specific processes.

This study investigates the role of BRC-1-BRD-1 in male meiosis of C. elegans, showing it regulates DSB processing and inhibits supernumerary crossovers, contrasting with its role in female meiosis.

The paper describes a method to generate and validate recombinant monoclonal antibodies for neuroscience research, enabling multiplex immunolabeling of brain tissue.