Author

Dennis Hoffmann

University of MünsterORCID 0000-0002-2734-9902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:imaging· 1

Frequent Co-Authors

Arndt F. SiekmanniD· 1 shared Benjamin D. SimonsiD· 1 shared Elvin Leonard· 1 shared Erez RaziD· 1 shared Laura ErmlichiD· 1 shared Lucas Kühl· 1 shared Martin LangeiD· 1 shared Michal Reichman‐FriediD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Arndt F. SiekmannORCID

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2 papers

Recent·Most cited

Corrections in single cell migration path in vivo are controlled by pulses in polar Rac1 activation

Dennis Hoffmann, Tal Agranov, Lucas Kühl, Laura Ermlich, Michal Reichman‐Fried, Benjamin D. Simons, Nir S. Gov, Erez Raz

The paper investigates how periodic changes in cell polarity during migration are controlled by pulsations in Rac1 activity in live zebrafish embryos.

Current Biology · Aug 21, 2025Peer-reviewedCell Biology

Distinct Vegfa isoforms control endothelial cell proliferation through PI3 kinase signalling mediated regulation of cdkn1a/p21

Martin Lange, Elvin Leonard, Nils Ohnesorge, Dennis Hoffmann, Susana Rocha, Rui Benedito, Arndt F. Siekmann

This study shows that Vegfa isoforms differentially regulate endothelial cell proliferation via PI3K signaling, independent of MAPK (ERK) activation in zebrafish.

Developmental Biology · Mar 23, 2022Peer-reviewedDevelopmental Biology