Author

Christopher A. LeClair

National Center for Advancing Translational SciencesORCID 0000-0002-2746-5938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1

Frequent Co-Authors

Anton M. SimeonoviD· 1 shared Carlos A. TristaniD· 1 shared Chaitali Sen· 1 shared Chandrasekhar GurramkondaiD· 1 shared Claudia A. DoegeiD· 1 shared Daniel F. BennettiD· 1 shared David CastellanoiD· 1 shared Dingyin TaoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Anton M. SimeonovORCID

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2 papers

Recent·Most cited

Developmental BiologyStem Cell ReportsPeer-reviewedJun 11, 2026

Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders

Vukasin M. Jovanovic, Narisu Narisu, Lori L. Bonnycastle…·Carlos A. Tristan

This paper describes a scalable method to differentiate human pluripotent stem cells into hypothalamic arcuate neurons, which can model metabolic and reproductive disorders.

DOI 10.1016/j.stemcr.2026.102958

humanATAC-seq

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Synthetic BiologyNew BiotechnologyPeer-reviewedJun 20, 2025

On-demand insulin manufacturing using cell-free systems with an "on-column" conversion approach

Shayan G. Borhani, Max Z. Levine, Chandrasekhar Gurramkonda…·Govind Rao

This paper develops a cell-free system for rapid insulin production using on-column conversion, improving accessibility and reducing supply chain strain.

3 citations

experimental assay

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