Cell BiologybioRxivPreprint
NET1/ARHGEF8 is a mechanosensitive Guanine Exchange Factor controlling vascular smooth muscle cells' contractility
Mary-Adel Mrad, Surya Prakash Rao Batta, Virginie Vignard…·Anne-Clémence Vion
This study identifies NET1/ARHGEF8 as a mechanosensitive RhoGEF that regulates vascular smooth muscle cell contractility and adhesion in response to cyclic stretch.
DOI 10.1101/2025.11.26.690669